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COA of ALC-0315
Description:
ALC-0315 is an ionisable aminolipid that used for mRNA compaction and aids mRNA cellular delivery. ALC-0315 can be used to form lipid nanoparticle (LNP) delivery vehicles.
Chemical Information
| Catalog | Featured products |
|---|---|
| Purity of current batch | >99% |
| CAS | 2036272-55-4 |
| Molecular Weight (MW) | 766.27 |
| Molecular Formula | C48H95NO5 |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Handling:
Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months.
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Reference:
[1]. Lutz J, et, al. Novel rsv rna molecules and compositions for vaccination. WO2019202035A1.
[2]. Kulkarni JA, et, al. Lipid Nanoparticles Enabling Gene Therapies: From Concepts to Clinical Utility. Nucleic Acid Ther. 2018 Jun;28(3):146-157.