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COA of XNW34017
Description:
XNW34017 is a PROTAC targeting Aurora A. It binds both Aurora A and the E3 ligase CRBN, leading to ubiquitination of Aurora A by CRBN, followed by specific degradation via the ubiquitin-proteasome system (UPS). This results in cell cycle arrest and apoptosis, thereby killing tumor cells.
Chemical Information
| Catalog | DC68065 |
|---|---|
| Purity of current batch | >98% |
| Molecular Weight (MW) | |
| Molecular Formula | |
| Storage | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
Handling:
Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months.
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.