113-O12B Datasheet DC Chemicals

Description	113-O12B is a disulfide bond-containing ionizable cationic lipidoid. 113-O12B LNP, an LN-targeting LNP delivery system, is developed for a mRNA cancer vaccine. The 113-O12B/mRNA shows enhanced expression in APCs compared with ALC-0315/mRNA, indicating the LN-specific targeting ability.
Cat.No	DC80065
Name	113-O12B

Chemical Properties

CAS	2803699-72-9
Formula	C57H111N3O8S8
MW	1223.03
Storage	-20

References

Lipid nanoparticle-mediated lymph node–targeting delivery of mRNA cancer vaccine elicits robust CD8+T cell response. PNAS, (2022), 119, 34, e2207841119.

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