EHP-101 (VCE- 004.8) Datasheet DC Chemicals
Description EHP-101 (VCE-004.8) is an orally active, specific PPARγ and CB2 receptor dual agonist. EHP-101 inhibits prolyl-hydroxylases (PHDs) and activates the HIF pathway. EHP-101 attenuates adipogenesis and prevents diet-induced obesity. EHP-101 (20 mg/kg/day; i.p.; for 3 weeks) induces a significant reduction in body weight gain, total fat mass, adipocyte volume and plasma triglycerides levels in HFD mice.
Cat.No DC57061
Name EHP-101 (VCE- 004.8)

Chemical Properties

CAS 1818428-24-8
Formula C28H35NO3
MW 433.5824
Storage Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

References

VCE-004.8 ( injection; 20 mg/kg/day; for 3 weeks) induces a significant reduction in body weight gain, total fat mass, adipocyte volume and plasma triglycerides levels in HFD mice. VCE-004.8 can also significantly ameliorate glucose tolerance, reduce leptin levels (a marker of adiposity) and increase adiponectin and incretins (GLP-1 and GIP) levels[1].
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