(1S,2S)-Bortezomib Datasheet DC Chemicals

Description	(1S,2S)-Bortezomib is an enantiomer of Bortezomib. Bortezomib is a cell-permeable, reversible, and selective proteasome inhibitor, and potently inhibits 20S proteasome (Ki of 0.6 nM) by targeting a threonine residue. Bortezomib disrupts the cell cycle, induces apoptosis, and inhibits NF-κB. Bortezomib is an anti-cancer agent and the first therapeutic proteasome inhibitor to be used in humans.
Cat.No	DC28847
Name	(1S,2S)-Bortezomib

Chemical Properties

CAS	1132709-14-8
Formula	C19H25BN4O4
MW	384.24
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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