Lipid CAD9 (3-A2-7b) Datasheet DC Chemicals
Description Lipid CAD9 (3-A2-7b is a cationic degradable (CAD) lipid. 3-A2-7b formulated LNP, LNP-CAD9, can deliver FLuc mRNA to the lungs in vivo. LNP-CAD9 co-delivering Cas9 mRNA/VEGFR2 single guide RNA (sgRNA) effectively induces VEGFR2 knock out in lung endothelial cells of female mice.
Cat.No DC60566
Name Lipid CAD9 (3-A2-7b)

Chemical Properties

CAS
Formula
MW
Storage 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

female preclinical models-Nature Communication-22 January 2024-Lulu Xue,Drew Weissman3,5 & Michael J. Mitchell
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