4E1rcat Datasheet DC Chemicals

Description	4E1RCat is an inhibitor of protein translation that has been shown to prevent eIF4E:eIF4G and eIF4E:4E-BP1 interaction.
Cat.No	DC8245
Name	4E1rcat

Chemical Properties

CAS	328998-25-0
Formula	C28H18N2O6
MW	478.45232
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

[1]. Cencic R, et al. Reversing chemoresistance by small molecule inhibition of the translation initiation complex eIF4F. Proc Natl Acad Sci U S A. 2011 Jan 18;108(3):1046-51. [2]. Shuda M, et al. CDK1 substitutes for mTOR kinase to activate mitotic cap-dependent protein translation. Proc Natl Acad Sci U S A. 2015 May 12;112(19):5875-82.

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