10-Deacetylpaclitaxel Datasheet DC Chemicals
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Cat.No DC10857
Name 10-Deacetylpaclitaxel

Chemical Properties

CAS 78432-77-6
Formula C45H49NO13
MW 811.8695
Storage 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Biological activity

Description CAS NO.：78432-77-6
Product Name：10-Desacetylpaclitaxel
Synonyms：Deacetyltaxol;10-Desacetyltaxol;10-O-Deacetyltaxol;10-Desacetyl Paclitaxel;7-EPI-10-DEACETYL PACLITAXEL;b-(Benzoylamino)-a-hydroxy-benzenepropanoic acid [2aR-[2aa,4b,4ab,6b,9a(aR*,bS*),11a,12a,12aa,12ba]]-12b-(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,6,11-trihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl ester;10-DAT;10-Deacetyltaxol;10-DESACETYL PACLITAXEL,WHITE TO OFF-WHITE SOLID;10-deacetyl-paclitaxel;10-Deacetylpaclitaxel;7-epi-10-deacetyltaxol;b-(Benzoylamino)-a-hydroxy-benzenepropanoic acid [2aR-[2aa,4b,4ab,6b,9a(aR*,bS*),11a,12a,12aa,12ba]]-12b-(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10;[ "" ];N2123;[(1S,2S,3R,4S,7R,9R,10S,12S,15S)-4-Acetyloxy-15-[(2R,3S)-3-benzamido-2-hydroxy-3-phenylpropanoyl]oxy
EINEC:
Molecular Formula：C45H49NO13
Molecular Weight：811.8695
Target:
In Vivo
In Vitro
Kinase Assay
Cell Assay
Animal Administration

References

[1]. 19-Hydroxybaccatin III, 10-deacetylcephalomannine, and 10-deacetyltaxol: new antitumor taxanes from Taxus wallichiana. J Nat Prod. 1981 May-Jun;44(3):312-9. [2]. Michel Colin, et al. Process for the preparation of taxol and 10-deacetyltaxol. US4857653A. [3]. Helson L. Cephalomannine and 10-deacetyltaxol cytotoxicity in human glial and neuroblastoma cell-lines. Int J Oncol. 1993 Feb;2(2):297-9.
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