Pinacidil monohydrate (Pinacidil hydrate) Datasheet DC Chemicals
Description
Pinacidil monohydrate, an antihypertensive drug, is a potassium channel activator.
Cat.No
DC12096
Name
Pinacidil monohydrate (Pinacidil hydrate)
Chemical Properties
CAS
85371-64-8
Formula
C13H21N5O
MW
263.338742017746
Storage
2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
References
[1]. Buckle DR, et al. Relaxant effects of the potassium channel activators BRL 38227 and pinacidil on guinea-pig and human airway smooth muscle, and blockade of their effects by glibenclamide and BRL 31660. Pulm Pharmacol. 1993 Mar;6(1):77-86.
[2]. Bareggi SR, et al. Pharmacodynamics and pharmacokinetics of pinacidil in normotensive volunteers after repeated doses of a new slow-release tablet formulation. Arzneimittelforschung. 1999 Jan;49(1):21-5.
[3]. Gollasch M, et al. Pinacidil relaxes porcine and human coronary arteries by activating ATP-dependent potassium channels in smooth muscle cells. J Pharmacol Exp Ther. 1995 Nov;275(2):681-92.
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