9-hydroxyellipticine HCl Datasheet DC Chemicals
Description 9-hydroxyellipticine, also known as IGIG 929 and LS133324, is a potent cytotoxic and antitumor agent. Structurally, 9-hydroxyellipticine is a 9-hydroxy derivative of ellipticine. The hydroxy group in 9-hydroxyellipticines increases the apparent affinity for DNA, stabilisation of toposiomerase II-DNA cleavable complex, oxidation to reactive quinone-imine intermediates, phosphorylation of p53 suppressor proteins and cytotoxicity relative to the parent ellipticines.
Cat.No DC32500
Name 9-hydroxyellipticine HCl

Chemical Properties

CAS 52238-35-4
Formula C17H14N2O
MW 262.31
Storage

References

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