SKL2001 Datasheet DC Chemicals

Description	SKL2001 is an agonist of the Wnt/β-catenin pathway, with anti-cancer activity.
Cat.No	DC10888
Name	SKL2001

Chemical Properties

CAS	909089-13-0
Formula	C14H14N4O3
MW	286.29
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

[1]. Gwak J, et al. Small molecule-based disruption of the Axin/β-catenin protein complex regulates mesenchymal stem cell differentiation. ell Res. 2012 Jan;22(1):237-47. [2]. Ohashi W, et al. SKL2001 suppresses colon cancer spheroid growth through regulation of the E-cadherin/β-Catenin complex. Biochem Biophys Res Commun. 2017 Nov 25;493(3):1342-1348.

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