AA3-DLin Datasheet DC Chemicals

Description	AA3-DLin is an ionizable cationic amino lipid (pKa = 5.8) that has been used in combination with other lipids in the formation of lipid nanoparticles (LNPs) for the delivery of mRNA.LNPs containing AA3-DLin and encapsulating mRNA for the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike glycoprotein induce immunogenicity in mice.
Cat.No	DC82101
Name	AA3-DLin

Chemical Properties

CAS	2832061-33-1
Formula	C44H78N2O4
MW	699.1
Storage

References

1. Li, Z., Zhang, X.-Q., Ho, W., et al. Enzyme-catalyzed one-step synthesis of ionizable cationic lipids for lipid nanoparticle-based mRNA COVID-19 vaccines. ACS Nano 16(11), 18936–18950 (2022).

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