2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Biological activity
Description
CAS NO.：1644545-52-7 Product Name：Vorasidenib Synonyms：Vorasidenib;AG881;789Q85GA8P;6-(6-chloropyridin-2-yl)-N2,N4-bis((R)-1,1,1-trifluoropropan-2-yl)-1,3,5-triazine-2,4-diamine;6-(6-chloropyridin-2-yl)-N2,N4-bis[(2R)-1,1,1-trifluoropropan-2-yl]-1,3,5-triazine-2,4-diamine;9UO;Vorasidenib [INN];Vorasidenib [USAN];Vorasidenib (AG881);Vorasidenib (USAN/INN);AG 881 [WHO-DD];GTPL10663;BDBM279948;NSC803600;s8611;US10028961, C EINEC: Molecular Formula：C14H13CLF6N6 Molecular Weight：414.7366
Target:
In Vivo
In Vitro
Vorasidenib has recently entered phase 1 clinical trials in hematologic (NCT02492737) and solid malignancies (NCT02481154) in patients with either an IDH1 or an IDH2 mutation. Preclinical studies have suggested that Vorasidenib fully penetrates the blood-brain barrier and may be a more effective option for patients with IDH1/2 mutated glioma[1].
Kinase Assay
Cell Assay
Animal Administration
References
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