2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Biological activity
Description
CAS NO.：118409-57-7 Product Name：Tyrphostin A23 Synonyms：Propanedinitrile,2-[(3,4-dihydroxyphenyl)methylene]-;Tyrphostin 23;Tyrphostin A23;AG-18;AG-18 (AG18, Tyrphostin A23, RG-50810);(3,4-Dihydroxybenzylidene)malononitrile RG-50810;2-[(3,4-dihydroxyphenyl)methylidene]propanedinitrile;RG 50810;RG-50810;AG18;(3,4-Dihydroxybenzylidene)malononitrile;2-(3,4-Dihydroxybenzylidene)malononitrile;AG 18 (pharmaceutical);RG 50858;TX 825;Tyrphostin AG 18;Tyrphostin AG 1;AG-18(RG-50810);Tyrphostin A 23;AG18, >=98%;AG 18;Tyrphostin AG18;Tyrphostin RG50810;alpha-Cyano-(3,4-dihydroxy)cinnamonitrile;(3,4-Dihydroxyphenyl)methylene propanedinitrile;RV0GCD31OJ;C10H6N2O2;(3,4-dihydroxybenzylidene)propanedinitrile;DS EINEC: Molecular Formula：C10H6N2O2 Molecular Weight：186.1668
Target:
In Vivo
In Vitro
10 μM tyrphostin 23 causes significant inhibition of the cell proliferation caused by 1 nM and 1μM ghrelin[2]. Tyrphostin 23 (T23) is a well-known inhibitor of protein tyrosine kinases and has been considered as potential anti-cancer drug. T23 is reported to acutely stimulate the glycolytic flux in primary cultured astrocytes. Tyrphostin 23 stimulates glycolytic flux in cultured astrocytes. Mitochondrial metabolism of brain astrocytes is accelerated by Tyrphostin 23 exposure[3].
Kinase Assay
Cell Assay
Animal Administration
References
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