ALLO-1 Datasheet DC Chemicals

Description	ALLO-1 is a SMO antagonist that inhibits both wild-type (IC50 = 50 nM) and mutant SMO, including the D473H SMO mutant (IC50s = 300-1000 nM).
Cat.No	DC8570
Name	ALLO-1

Chemical Properties

CAS	37468-32-9
Formula	C17H15CLN2O2
MW	314.766203165054
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

[1]. Sato M, et al. The autophagy receptor ALLO-1 and the IKKE-1 kinase control clearance of paternal mitochondria in Caenorhabditis elegans. Nat Cell Biol. 2018 Jan;20(1):81-91.

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