AV-412(MP-412) Datasheet DC Chemicals

Description	AV-412(MP-412) is a potent dual inhibitor of EGFR and ErbB2(IC50=19 nM) tyrosine kinases, including the mutant EGFR(L858R IC50=0.51 nM, T790M IC50=0.79 nM); inhibits autophosphorylation of EGFR and ErbB2 with IC(50) of 43 and 282 nM, respectively.
Cat.No	DC8253
Name	AV-412(MP-412)

Chemical Properties

CAS	451492-95-8
Formula	C27H28CLFN6O
MW	507
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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