AX20017 Datasheet DC Chemicals

Description	AX20017 is a small-molecule protein kinase G (PknG) inhibitor with an IC50 of 0.39 μM.
Cat.No	DC10412
Name	AX20017

Chemical Properties

CAS	329221-38-7
Formula	C13H16N2O2S
MW	264.34
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

[1]. Walburger A, et al. Protein kinase G from pathogenic mycobacteria promotes survival within macrophages. Science. 2004 Jun 18;304(5678):1800-4. [2]. Santhi N, et al. Insights from the molecular docking of withanolide derivatives to the target protein PknG from Mycobacterium tuberculosis. Bioinformation. 2011;7(1):1-4. [3]. Scherr N, et al. Structural basis for the specific inhibition of protein kinase G, a virulence factor of Mycobacterium tuberculosis. Proc Natl Acad Sci U S A. 2007 Jul 17;104(29):12151-6.

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