AZD5153 6-Hydroxy-2-naphthoic acid Datasheet DC Chemicals

Description	AZD5153 6-Hydroxy-2-naphthoic acid is the 6-Hydroxy-2-naphthoic acid of AZD5153. AZD5153 is a potent, selective, and orally available BET/BRD4 bromodomain inhibitor; disrupts BRD4 with an IC50 of 1.7 nM.
Cat.No	DC10288
Name	AZD5153 6-Hydroxy-2-naphthoic acid

Chemical Properties

CAS	1869912-40-2
Formula	C36H41N7O6
MW	667.75
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

[1]. Rhyasen GW, et al. AZD5153: A Novel Bivalent BET Bromodomain Inhibitor Highly Active against Hematologic Malignancies. Mol Cancer Ther. 2016 Nov;15(11):2563-2574.

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