Ac-DEVD-pNA(Caspase-3 Substrate) Datasheet DC Chemicals
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Cat.No DC11458
Name Ac-DEVD-pNA(Caspase-3 Substrate)

Chemical Properties

CAS 189684-50-2
Formula C26H34N6O13
MW
Storage 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Biological activity

Description CAS NO.：189684-50-2
Product Name：L-a-Asparagine,N-acetyl-L-a-aspartyl-L-a-glutamyl-L-valyl-N-(4-nitrophenyl)-
Synonyms：L-a-Asparagine,N-acetyl-L-a-aspartyl-L-a-glutamyl-L-valyl-N-(4-nitrophenyl)-
EINEC:
Molecular Formula：C26H34N6O13
Molecular Weight：
Target:
In Vivo
In Vitro Ac-DEVD-pNA is a colorimetric substrate for caspase-3 (CPP32) (Km=9.7μM) and related cysteine proteases. It is also a substrate for caspase-6, caspase-7, caspase-8, and caspase-10. The sequence is based on PARP (poly(ADPribose) polymerase) cleavage site Asp216 for caspase-3. Cleavage is monitored colorimetrically at 405nm
Kinase Assay
Cell Assay
Animal Administration

References

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