| Description |
Adalimumab (anti-TNF-alpha) is the first fully human, recombinant IgG1 monoclonal antibody that specifically targets human TNF-alpha. |
| Cat.No |
A001 |
| Name |
Adalimumab |
Chemical Properties
| CAS |
331731-18-1 |
|
| Synonyms |
Unii-fys6T7F842;Adalimumab;D2E7;Humira;Immunoglobulin G1, anti-(human tumor necrosis factor) (human monoclonal D2E7 heavy chain), disulfide with human monoclonal D2E7 light chain, dimer;D 2E7;Sivelestat;ONO5046;2-[[2-[[4-(2,2-dimethylpropanoyloxy)phenyl]sulfonylamino]benzoyl]amino]acetic acid;LY544349;C20H22N2O7S;EI546;N-(2-(4-(2,2-Dimethylpropionyloxy)phenylsulfonylamino)benzoyl)aminoacetic acid;DWI62G0P59;EI546;LY544349;ONO5046;2-(2-(4-(pivaloyloxy)phenylsulfonamido)benzamido)acetic acid;2-[(2-{4-[(2,2-dimethylpropanoyl)oxy]benzenesulfonamido}phenyl)formamido]acetic acid;N-[2-(N'-(Carboxymethyl)-aminocarbonyl)-p;o-(p-Hydroxybenzenesulfonamido)hippuric acid, pivalate (ester);SIVELESTAT [MI];(2-((4-(Pivaloyloxy)phenyl)sulfonamido)benzoyl)glycine;331731-18-1;BDBM50084637;SIVELESTAT [MART.];s8136;BRD-K02152879-414-02-1;CCG-269065;5134A;D03788;Sivelestat (USAN/INN);A11497;SIVELESTAT [WHO-DD];BCP09708;CHEBI:135704;LY 544349;NCGC00346934-01;SIVELESTAT [INN];Glycine, N-(2-(((4-(2,2-dimethyl-1-oxopropoxy)phenyl)sulfonyl)amino)benzoyl)-;ABT-D2E7;NCGC00263570-03;NS00071648;Ono-5046;MFCD00889071;ONO5046;LY544349;EI546;EI 546;Elastase Inhibitor IV - CAS 127373-66-4;Q5646925;2,2-Dimethyl-propionic acid 4-[2-(carboxymethyl-carbamoyl)-phenylsulfamoyl]-phenyl ester(ONO-5046);Sivelestat [USAN];UNII-DWI62G0P59;Sivelestat (ONO-5046);AS-74843;US9073833, Sivelestat;SCHEMBL123221;Elastase Inhibitor IV;Ono-EI-600;LY-544349;GTPL6441;N-[2-(N'-(Carboxymethyl)-aminocarbonyl)-phenyl]-4-t-butylcarbonyloxybenzenesulfonamide;2,2-Dimethyl-propionic acid 4-[2-(carboxymethyl-carbamoyl)-phenylsulfamoyl]-phenyl ester;NCGC00263570-06;SDCCGSBI-0633759.P001;AKOS022176173;Sivelestat [USAN:INN];J-005486;127373-66-4;NCGC00263570-02;DB12863;CHEMBL76688;DTXSID9048304;AT42741;BRD-K02152879-414-01-3;HY-17443;Propanoic acid, 2,2-dimethyl-, 4-[[[2-[[(carboxymethyl)amino]carbonyl]phenyl]amino]sulfonyl]phenyl ester;BDBM166439;Anti-Human TNF-alpha, Human Antibody |
| pH value |
Corresponds to reference standard： PASS |
| Non-reduced CE-SDS |
98.7% |
| SEC-HPLC |
99.5% |
| Isoelectric Point |
Corresponds to reference standard |
| Bacterial Endotoxins Test |
＜1 EU/ml |
| Residual Proteins of Host Cell |
|
| Exogenous Residual DNA |
＜1 pg/mg |
| Residual protein A |
＜1 ng/mg |
| Biological Activity |
Compared with standard, the range ofbiological activity is 103% |
| Osmolality |
Corresponds to reference standard: PASS |
| Peptide mapping |
Corresponds to reference standard: PASS |
| N-terminal sequence |
Corresponds to reference standard:PASS |
References
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