Antibiotic 1166C Datasheet DC Chemicals
Description Hygrolidin is a macrocyclic lactone that inhibits proliferation of DLD-1 colon cancer, LNCaP prostate cancer, and K562 leukemia cells. Hygrolidin induces the expression and levels of p21 in DLD-1 cells, but not WI-38 fibroblasts, and leads to cell accumulation in the G1 and S phases without inducing apoptosis. It has antiparasitic activity against T. cruzi, L. donovani, and T. b. brucei but also induces cytotoxicity in HepG2 cells.
Cat.No DC36379
Name Antibiotic 1166C

Chemical Properties

CAS
Formula C38H58O11
MW 690.87
Storage

References

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