BAY-1895344 HCl(Elimusertib) Datasheet DC Chemicals
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Cat.No DC10526
Name BAY-1895344 HCl(Elimusertib)

Chemical Properties

CAS 1876467-74-1
Formula C20H22CLN7O
MW 411.89
Storage 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Biological activity

Description
Target:
In Vivo BAY-1895344 shows potent anti-tumor efficacy in monotherapy in a variety of xenograft models of ovarian and colorectal cancer, and causes complete tumor remission in mantle cell lymphoma models[2].
In Vitro BAY-1895344 potently inhibits the proliferation of a broad spectrum of human tumor cell lines with a median IC50 of 78 nM[1]. BAY-1895344 potently suppresses hydroxyurea-induced H2AX phosphorylation (IC50, 36 nM)[1].
Kinase Assay
Cell Assay
Animal Administration

References

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