BDTX-189 Datasheet DC Chemicals

Description	BDTX-189 is a potent, orally active and selective inhibitor of allosteric EGFR and HER2 oncogenic mutations, includes EGFR/HER2 exon 20 insertion mutants. BDTX-189 shows KDs of 0.2, 0.76, 13 and 1.2 nM for EGFR, HER2, BLK and RIPK2, reapectively. Anticancer activity.
Cat.No	DC41015
Name	BDTX-189

Chemical Properties

CAS	2414572-47-5
Formula	C29H29CLN6O4
MW	561.03
Storage	Powder-20°C3 years4°C2 yearsIn solvent-80°C6 months-20°C1 month

References

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