BI-0115 Datasheet DC Chemicals
Description BI-0115 is a selective small molecule inhibitor of LOX-1 that blocks cellular uptake of oxLDL. BI-0115 binding triggers receptor inhibition by formation of dimers of the homodimeric ligand binding domain. The structure of LOX-1 bound to BI-0115 shows that inter-ligand interactions at the receptor interfaces are key to the formation of the receptor tetramer thereby blocking oxLDL binding.
Cat.No DC59015
Name BI-0115

Chemical Properties

CAS 4929-23-1
Formula C15H14CLN3O
MW 287.74
Storage -20

References

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