BMS-181176 Datasheet DC Chemicals
Description Becatecarin, also known as BMY-27557, XL119 and BMS-181176, is a synthetic diethylaminoethyl analogue of the indolocarbazole glycoside antineoplastic antibiotic rebeccamycin. Becatecarin intercalates into DNA and stabilizes the DNA-topoisomerase I complex, thereby interfering with the topoisomerase I-catalyzed DNA breakage-reunion reaction and initiating DNA cleavage and apoptosis.
Cat.No DC31210
Name BMS-181176

Chemical Properties

CAS 119673-08-4
Formula C33H34CL2N4O7
MW 669.55166
Storage

References

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