BMS-986251 Datasheet DC Chemicals

Description	BMS-986251 is an orally active and selective RORγt inverse agonist with an EC50 of 12 nM for RORγt GAL4. BMS-986251 inhibits IL-17 with an EC50 of 24 nM in human whole blood assay. BMS-986251 demonstrates robust efficacy in mouse acanthosis and Imiquimod-induced models (preclinical models of psoriasis).
Cat.No	DC40965
Name	BMS-986251

Chemical Properties

CAS	2460133-35-9
Formula	C30NO5F8SH29
MW	667.6072
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.

References

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