BPTU Datasheet DC Chemicals

Description	BPTU is an Allosteric antagonist of P2Y1 (EC50 = 0.06-0.3 μM).
Cat.No	DC10618
Name	BPTU

Chemical Properties

CAS	870544-59-5
Formula	C23H22F3N3O3
MW	445.434296131134
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

[1]. Ma?é N, et al. BPTU, an allosteric antagonist of P2Y1 receptor, blocks nerve mediated inhibitory neuromuscular responses in the gastrointestinal tract of rodents. Neuropharmacology. 2016 Nov;110(Pt A):376-385. [2]. Verrijk R, et al. Pharmacokinetics in melanoma-bearing mice of 5-dihydroxyboryl-6-propyl-2-thiouracil (BPTU), a candidate compound for boron neutron capture therapy. Br J Cancer. 1994 Apr;69(4):641-7.

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