BRD7552 Datasheet DC Chemicals
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Cat.No DC8409
Name BRD7552

Chemical Properties

CAS 1137359-47-7
Formula C33H33N3O15
MW 711.6262
Storage 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Biological activity

Description CAS NO.：1137359-47-7
Product Name：Ethyl 4-(((((2R,3R,4S,5R,6S)-4,5-bis((benzo[d][1,3]dioxol-5-ylcarbamoyl)oxy)-2-(hydroxymethyl)-6-methoxytetrahydro-2H-pyran-3-yl)oxy)carbonyl)amino)benzoate
Synonyms：BRD 7552;BRD-7552;Ethyl 4-(((((2R,3R,4S,5R,6S)-4,5-bis((benzo[d][1,3]dioxol-5-ylcarbamoyl)oxy)-2-(hydroxymethyl)-6-methoxytetrahydro-2H-pyran-3-yl)oxy)carbonyl)amino)benzoate;BRD7552;PK04Pur_000261;AOB2459;BRD7552, >=98% (HPLC);S7363;PK04_094072;A14957;1040E1_000045;alpha-D-Glucopyranoside, methyl, 2,3-bis(N-1,3-benzodioxol-5-ylcarbamate) 4-[N-[4-(ethoxycarbonyl)phenyl]carbamate];e
EINEC:
Molecular Formula：C33H33N3O15
Molecular Weight：711.6262
Target:
In Vivo
In Vitro BRD7552 upregulates PDX1 expression in both primary human islets and ductal cells, and induces epigenetic changes in the PDX1 promoter consistent with transcriptional activation. BRD7552 increases PDX1 mRNA levels by 2- to 4-fold, with a maximal effect at 5 μM and the expression of MAFA. BRD7552 increases PDX1 expression in mouse αTC cells but not βTC cells. Treatment of PANC-1 cells with BRD7552 causes a dose-dependent increase in insulin mRNA expression. [1]
Kinase Assay
Cell Assay
Animal Administration

References

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