BTC-8 (BTC 8;BTC8) Datasheet DC Chemicals
Description A derivative of BAM-7 that acts as a nove potent, direct activator of Bax with EC50 of 700 nM; inhibits GBM cell proliferation, arrests the cell cycle, and induces apoptosis through the induction of mitochondrial membrane permeabilization; also blocks proliferation and self-renewal of GSCs and induces their apoptosis; sensitizes both GBM cells and GSCs to the alkylating agent Temozolomide.
Cat.No DC29236
Name BTC-8 (BTC 8;BTC8)

Chemical Properties

CAS
Formula C26H27N5O3
MW 457.534
Storage 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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