B-Raf inhibitor 1 Datasheet DC Chemicals

Description	B-Raf inhibitor 1 is a potent and selective B-Raf inhibitor with cell IC50s of 0.31 uM and 2 nM for A375 proliferation and A375 p-ERK respectively.
Cat.No	DC8921
Name	B-Raf inhibitor 1

Chemical Properties

CAS	1093100-40-3
Formula	C26H19CLN8
MW	478.9357
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

[1]. Wang X, et al. Conformation-specific effects of Raf kinase inhibitors. J Med Chem. 2012 Sep 13;55(17):7332-41.

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