Bevacizumab (anti-VEGF) is a humanized anti-VEGF monoclonal antibody which binds to and neutralizes all human VEGF-A isoforms and bioactive proteolytic fragments.
Cat.No
A005
Name
Bevacizumab
Chemical Properties
CAS
216974-75-3
Synonyms
pH value
Corresponds to reference standard： PASS
Non-reduced CE-SDS
98.9%
SEC-HPLC
99.4%
Isoelectric Point
Corresponds to reference standard:PASS
Bacterial Endotoxins Test
＜1 EU/ml
Residual Proteins of Host Cell
Exogenous Residual DNA
＜1 pg/mg
Residual protein A
＜1 ng/mg
Biological Activity
Compared with standard, the range of biological activity is 113%
Osmolality
Corresponds to reference standard: PASS
Peptide mapping
Corresponds to reference standard: PASS
N-terminal sequence
Corresponds to reference standard:PASS
References
[1]. Liu W, et al. Effect of Avastin on the migration and invasion of pterygium fibroblasts. Eye Sci. 2014;29(4):214-218.
[2]. Lee AL, et al. Injectable biodegradable hydrogels from vitamin D-functionalized polycarbonates for the delivery of avastin with enhanced therapeutic efficiency against metastatic colorectal cancer. Biomacromolecules. 2015;16(2):465-475.
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