Brevetoxin B Datasheet DC Chemicals

Description	Brevetoxin B (Brevetoxin-2; PbTx-2) is a polyketide neurotoxin produced by Karenia species and other dinoflagellates. Brevetoxin B binds to site 5 on the alpha subunit of voltage-gated sodium channels (IC50=15 nM) on neurons at the neuromuscular junction, causing the channel to open irreversibly at potentials more negative than normal, discharging action potentials repetitively. Brevetoxin B is ichthyotoxic at nanomolar concentrations and is responsible for an illness described as neurotoxic shellfish poisoning.
Cat.No	DC40337
Name	Brevetoxin B

Chemical Properties

CAS	79580-28-2
Formula	C50H70O14
MW	895.08
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.

References

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