C7280948 Datasheet DC Chemicals

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Cat.No	DC7379
Name	C7280948

Chemical Properties

CAS	587850-67-7
Formula	C14H16N2O2S
MW	276.35
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Biological activity

Description
Target:	PRMT1
In Vivo
In Vitro	Especially arginine methyltransferases also target non-histone protein substrates and are therefore often called protein methyltransferases (PRMTs). The subtype PRMT1 has been linked to the activation of estrogen and androgen receptors and therefore may represent a new treatment option for hormone-dependent cancer. C-7280948 is a inhibitor, which is available for PRMT1.
Kinase Assay
Cell Assay
Animal Administration

References

[1]. Bissinger EM, et al. Acyl derivatives of p-aminosulfonamides and dapsone as new inhibitors of the arginine methyltransferase hPRMT1. Bioorg Med Chem. 2011 Jun 15;19(12):3717-3731.

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