CCT007093 Datasheet DC Chemicals

Description	CCT007093 is a potent PPM1D (WIP1) inhibitor with IC50 of 8.4 μM.
Cat.No	DC7803
Name	CCT007093

Chemical Properties

CAS	176957-55-4
Formula	C15H12OS2
MW	272.39
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

[1]. Rayter S, et al. A chemical inhibitor of PPM1D that selectively kills cells overexpressing PPM1D. Oncogene. 2008 Feb 14;27(8):1036-44. [2]. Buss MC, et al. HDM2 promotes WIP1-mediated medulloblastoma growth. Neuro Oncol. 2012 Apr;14(4):440-58. [3]. Lee JS, et al. Off-target response of a Wip1 chemical inhibitor in skin keratinocytes. J Dermatol Sci. 2014 Feb;73(2):125-34.

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