Avadomide hydrochloride Datasheet DC Chemicals
Description Avadomide hydrochloride (CC-122 hydrochloride), the salt form of Avadomide (HY-100507), is an orally bioavailable cereblon-targeting agent that exerts potent antitumor and immunomodulatory effects. By modulating cereblon E3 ubiquitin ligase activity, this compound inhibits the NF-κB signaling pathway and induces G1 phase cell cycle arrest, ultimately triggering apoptosis in PDAC cancer cells.
Cat.No DC31426
Name Avadomide hydrochloride

Chemical Properties

CAS 1398053-45-6
Formula C14H15CLN4O3
MW 322.746901750565
Storage 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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