CHF-5074 Datasheet DC Chemicals
Description CHF-5074, also known as CSP-1103, is a γ-secretase modulator. CHF-5074 reduces Aβ42 and Aβ40 secretion, with an IC50 of 3.6 and 18.4 μM respectively. CHF5074 reduces brain beta-Amyloid pathology in a transgenic mouse model of Alzheimer's Disease without causing peripheral toxicity. CHF5074 is a non-steroidal anti-inflammatory derivative holding disease-modifying potential for the treatment of Alzheimer's disease.
Cat.No DC32774
Name CHF-5074

Chemical Properties

CAS 749269-83-8
Formula C16H11CL2FO2
MW 325.16
Storage

References

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