CID-2011756 Datasheet DC Chemicals
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Cat.No DC7253
Name CID-2011756

Chemical Properties

CAS 638156-11-3
Formula C22H21CLN2O3
MW 396.8667
Storage 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Biological activity

Description CAS NO.：638156-11-3
Product Name：5-(3-Chlorophenyl)-N-[4-(morpholin-4-ylmethyl)phenyl]furan-2-carboxamide
Synonyms：CID-2011756;5-(3-Chlorophenyl)-N-[4-morpholin-4-ymethyl)phenyl]furan-2-carboxamide;5-(3-Chlorophenyl)-N-(4-(morpholinomethyl)-phenyl)furan-2-carboxamide;5-(3-chlorophenyl)-N-[4-(morpholin-4-ylmethyl)phenyl]furan-2-carboxamide;CID 2011756;5-(3-chlorophenyl)-N-(4-(morpholinomethyl)phenyl)furan-2-carboxamide;MLS000557592;CID2011756;SMR000148508;5-(3-Chlorophenyl)-N-[4-(4-morpholinylmethyl)phenyl]-2-furancarboxamide;C22H21ClN2O3;5-(3-Chloro-phenyl)-furan-2-carboxylic acid (4-morpholin-4-ylmethyl-phenyl)-amide;Oprea1_481390;CH
EINEC:
Molecular Formula：C22H21CLN2O3
Molecular Weight：396.8667
Target:
In Vivo
In Vitro CID 2011756 is an ATP-competitive PKD1 inhibitor, with an IC50 of 3.2 µM. CID 2011756 decreases the phosphorylation of endogenous PKD1 Ser916 in LNCaP cancer cells with an EC50 of 10±0.7 µM. CID 2011756 also has cellular pan-PKD inhibitory effects, with IC50s of 0.6±0.1 µM and 0.7±0.2 µM for PKD2 and PKD3, respectively[1].
Kinase Assay
Cell Assay
Animal Administration

References

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