CLP-290 Datasheet DC Chemicals
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Cat.No DC12714
Name CLP-290

Chemical Properties

CAS 1181083-81-7
Formula C19H21FN4O3S
MW 404.46
Storage 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Biological activity

Description CAS NO.：1181083-81-7
Product Name：[5-Fluoro-2-[(Z)-(2-hexahydropyridazin-1-yl-4-oxo-thiazol-5-ylidene)methyl]phenyl] pyrrolidine-1-carboxylate
Synonyms：CLP-290,CLP 290,CLP290
EINECS:
Molecular Formula：C19H21FN4O3S
Molecular Weight：404.46
Target: KCC2[1]
In Vivo
In Vitro
Kinase Assay
Cell Assay
Animal Administration

References

[1]. Ferrini F, et al. Enhancing KCC2 function counteracts morphine-induced hyperalgesia. Sci Rep. 2017 Jun 20;7(1):3870. [2]. Gagnon M, et al. Chloride extrusion enhancers as novel therapeutics for neurological diseases. Nat Med. 2013 Nov;19(11):1524-8. [3]. Kim YB, et al. Excitatory GABAergic Action and Increased Vasopressin Synthesis in Hypothalamic Magnocellular Neurosecretory Cells Underlie the High Plasma Level of Vasopressin in Diabetic Rats. Diabetes. 2018 Mar;67(3):486-495.
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