COL-144 (Lasmiditan) succinate Datasheet DC Chemicals
Description Lasmiditan, also known as COL-144 and LY573144, is a novel, centrally acting, highly selective 5-HT(1F) receptor agonist (K1=2.21 μM) without vasoconstrictor activity that seemed effective when given as an intravenous infusion in a proof-of-concept migraine study. Lasmiditan showed efficacy in its primary endpoint, with a 2-hour placebo-subtracted headache response of 28.8%, though with frequent reports of dizziness, paresthesias, and vertigo.
Cat.No DC32393
Name COL-144 (Lasmiditan) succinate

Chemical Properties

CAS 439239-92-6
Formula C42H42F6N6O8
MW 872.808711528778
Storage 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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