COTI-2 Datasheet DC Chemicals

Description	COTI-2 is a small molecule candidate anti-cancer drug which can convert mutant p53 to wild-type conformation.
Cat.No	DC10657
Name	COTI-2

Chemical Properties

CAS	1039455-84-9
Formula	C19H22N6S
MW	366.4832
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

[1]. Duffy MJ, et al. Mutant p53 as a target for cancer treatment. Eur J Cancer. 2017 Sep;83:258-265. [2]. Salim KY, et al. COTI-2, a novel small molecule that is active against multiple human cancer cell lines in vitro and in vivo. Oncotarget. 2016 Jul 5;7(27):41363-41379.

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