CPI-613 Datasheet DC Chemicals
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Cat.No DC10591
Name CPI-613

Chemical Properties

CAS 95809-78-2
Formula C22H28O2S2
MW 388.5865
Storage 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Biological activity

Description CAS NO.:95809-78-2
Product Name:6,8-Bis(benzylthio)octanoic acid
Synonyms:CPI-613;6,8-Bis(benzylthio)octanoic Acid;6,8-Bis(benzylsulfanyl)octanoic acid;CPI 613;OCTANOIC ACID, 6,8-BIS[(PHENYLMETHYL)THIO]-;6,8-Bis[(phenylmethyl)thio]octanoic acid;Devimistat;AK174899;Octanoic acid, 6,8-bis((phenylmethyl)thio)-;MLS006010202;AOB1058;HMS3656L06;C22H28O2S2;BCP04663;s2776;BCP9000552;DB12109;SMR004701300;BCP0726000030;AB0035874;SW2202
EINEC:
Molecular Formula:C22H28O2S2
Molecular Weight:388.5865
Target:
In Vivo
In Vitro
Kinase Assay
Cell Assay
Animal Administration

References

[1]. Zachar Z, Marecek J, Maturo C et al. Non-redox-active lipoate derivates disrupt cancer cell mitochondrial metabolism and are potent anticancer agents in vivo. J Mol Med (Berl). 2011 Nov;89(11):1137-48. [2]. Lee KC, Shorr R, Rodriguez R et al. Formation and anti-tumor activity of uncommon in vitro and in vivo metabolites of CPI-613, a novel anti-tumor compound that selectively alters tumor energy metabolism. Drug Metab Lett. 2011 Aug;5(3):163-82. [3]. Safety and Effectiveness Study of CPI-613 to Treat Refractory or Relapsed Leukemia and Myelodysplastic Syndrome
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