CPI-455 Datasheet DC Chemicals

Description	CPI-455 is a specific, pan-KDM5 inhibitor with an IC50 of 10 nM for KDM5A. CPI-455 mediates KDM5 inhibition, elevates global levels of H3K4me3, and decreases the number of drug-tolerant persister cancer cells in multiple cancer cell line models treated with standard chemotherapy or targeted agents.
Cat.No	DC9858
Name	CPI-455

Chemical Properties

CAS	1628208-23-0
Formula	C16H15CLN4O
MW	314.7695
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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