Candesartan cilexetil Datasheet DC Chemicals
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Cat.No DC9185
Name Candesartan cilexetil

Chemical Properties

CAS 145040-37-5
Formula C33H34N6O6
MW 610.6597
Storage 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Biological activity

Description CAS NO.：145040-37-5
Product Name：Candesartan cilexetil
Synonyms：Candesartan cilexetil;1-[[(cyclohexyloxy)carbonyl]oxy]ethyl 2-ethoxy-1-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-1H-benzimidazole-7-carboxylate;1-(((Cyclohexyloxy)carbonyl)oxy)ethyl 1-((2'-(2H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-2-ethoxy-1H-benzo[d]imidazole-7-carboxylate;Cadesartan cilexetil;Candesartan Cilexeti;TCV-116;2-Ethoxy-3-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-3H-benzoimidazole-4-carboxylic acid 1-cyclohexyloxycarbonyloxy-ethyl ester;TCV116;2-ethoxy-1-[[2′-(2H-tetrazol-5-yl)[1,1′-biphenyl]-4-yl]methyl]-1H-Benzimidazole-7-carboxylic acid 1-[[(cyclohexyloxy)carbonyl]oxy]ethyl ester;TCY 116;Atacand;Blopress;Candestartan;Candesartanciletexil;Candesantan Cilexetil;CANDESARTAN CILEXITIL;Amias;Parapres;Kenzen;TCV 116;Candesartan (Cilexetil);CANDESARTAN CILEXTIL;candesartancilexetil;Candesartan cilexetil [USAN];C33H34N6O6;1H-Benzimidazolium, 7-carboxy-1-(2-((cyclohexylcarbonyl)oxy)ethyl)-2-ethoxy-1-(2'-(1H-tetrazol-5-yl)(1,1'-biphenyl)-4-yl)-, hydroxide, inner salt, (+-)-;2-Ethoxy-3-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-3H-benzoimidazole-4-carboxylic acid 1-cyclohexyloxycar
EINEC:
Molecular Formula：C33H34N6O6
Molecular Weight：610.6597
Target: Type-1 angiotensin II receptor
In Vivo
In Vitro
Kinase Assay
Cell Assay
Animal Administration

References

[1]. Pfeffer, M.A., et al., Effects of candesartan on mortality and morbidity in patients with chronic heart failure: the CHARM-Overall programme. Lancet, 2003. 362(9386): p. 759-66. [2]. Wada, T., et al., Comparison of the antihypertensive effects of the new angiotensin II (AT1) receptor antagonist candesartan cilexetil (TCV-116) and the angiotensin converting enzyme inhibitor enalapril in rats. Hypertens Res, 1996. 19(2): p. 75-81.
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