D-α-Hydroxyglutaric acid Datasheet DC Chemicals
Description D-α-Hydroxyglutaric acid ((R)-2-Hydroxypentanedioic acid) is the principal metabolite accumulating in neurometabolic disease D-2-hydroxyglutaric aciduria. D-α-Hydroxyglutaric acid is a weak competitive antagonist of α-ketoglutarate (α-KG) and inhibits multiple α-KG-dependent dioxygenases with a Ki of 10.87 mM. D-α-Hydroxyglutaric acid increases reactive oxygen species (ROS) production. D-α-Hydroxyglutaric acid binds and inhibits ATP synthase and inhibits mTOR signaling.
Cat.No DC40174
Name D-α-Hydroxyglutaric acid

Chemical Properties

CAS 13095-47-1
Formula C5H8O5
MW 148.11
Storage Please store the product under the recommended conditions in the Certificate of Analysis.

References

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