DAN 004 ( DAN004; DAN-004) Datasheet DC Chemicals
Description A small molecule Bax inhibitor that inhibits Bax/Bak oligomerization and prevents mitochondrial outer membrane permeabilization (MOMP) with IC50 of 0.7 uM; potently inhibits Bax/Bak-mediated apoptosis in HCT-116, BMK Cells, and primary cortical neurons, protects primary neurons against glutamate excitotoxicity.
Cat.No DC29237
Name DAN 004 ( DAN004; DAN-004)

Chemical Properties

CAS
Formula C26H28BRN3O2
MW 494.433
Storage 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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