DB1976 hydrochloride Datasheet DC Chemicals

Description	DB1976 hydrochloride is a selenophene analog of DB270 and a potent and cell-permeable fully efficacious PU.1 inhibitor. DB1976 hydrochloride potently inhibits PU.1 binding (IC50 of 10 nM) and strongly inhibits the PU.1/DNA complex (with high DB1976-λB affinity, KD of 12 nM) in vitro. DB1976 hydrochloride has apoptosis-inducing effect.
Cat.No	DC28946
Name	DB1976 hydrochloride

Chemical Properties

CAS	2369663-93-2
Formula	C20H18CL2N8SE
MW	520.28
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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