mutant EGFR inhibitor B30 Datasheet DC Chemicals

Description	mutant EGFR inhibitor B30 is a potent, selective, next-generation EGFR mutants inhibitor with IC50 of 1.1 and 7.2 nM for EGFRL858R and EGFRL858R/T790M/C797S, respectively.
Cat.No	DC10915
Name	mutant EGFR inhibitor B30

Chemical Properties

CAS	2225887-26-1
Formula	C31H38FN9O
MW	571.705
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

[1]. Zhang H, et al. Discovery of 2,4,6-trisubstitued pyrido[3,4-d]pyrimidine derivatives as new EGFR-TKIs. Eur J Med Chem. 2018 Mar 25;148:221-237.

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