MRL871 Datasheet DC Chemicals
Description MRL-871 (MRL871) is a potent, selective inhibitor of RORγt via allosteric inverse agonism, inhibits coactivator binding with IC50 of 7 nM; significantly reduces the IL17a mRNA levels in EL4 murine lymphoblast cell line at 10 uM.
Cat.No DC11047
Name MRL871

Chemical Properties

CAS 1392809-08-3
Formula C22H12CLF3N2O3
MW 444.794
Storage 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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