GNA002 Datasheet DC Chemicals
Description GNA002 (GNA-002) is a gambogenic acid (GNA) derivative that specifically and covalently binds to Cys668 within the EZH2-SET domain, trigges EZH2 degradation (IC50=1.1 uM) through COOH terminus of Hsp70-interacting protein (CHIP)-mediated ubiquitination.
Cat.No DC11070
Name GNA002

Chemical Properties

CAS 1385035-79-9
Formula C42H55NO8
MW 701.901
Storage 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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