Danicopan (ACH-4471) Datasheet DC Chemicals
Description Danicopan (ACH-4471, ACH-0144471) is a highly potent, orally active Factor D inhibitor with Kd of 0.54 nM, inhibits the proteolytic activity of purified Factor D against substrate Factor B in complex with C3b, blocking production of Bb fragment IC50 of 15 nM.
Cat.No DC11082
Name Danicopan (ACH-4471)

Chemical Properties

CAS 1903768-17-1
Formula C26H23BRFN7O3
MW 580.418
Storage 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

[1]. https://www.ncbi.nlm.nih.gov/pubmed/28416568
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